Urinary tract infections (UTIs) are among the most common bacterial infections in outpatient practice. Women are particularly susceptible: around 60% experience a UTI at least once in their lives, and 20–40% suffer from recurrent forms (two or more episodes within six months, or three or more per year).
One of the key factors in the development of UTIs is the adhesion of E. coli bacteria to the bladder walls. This is where cranberry comes in: its natural compounds prevent bacteria from attaching, reducing the risk of infection.
The largest meta-analysis to date, published in Cochrane Reviews in 2023, confirmed that regular consumption of cranberry juice or supplements reduces UTI risk in women by 53%.
🌿 Why Pacran®?
Pacran®, developed by Swiss company Givaudan, is a unique full-spectrum extract from whole cranberries — peel, flesh, seeds, and juice. This approach ensures not only a rich composition but also a broader and more consistent physiological effect.
Key benefits of Pacran®:
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🔬 Standardized: contains at least 1.5% proanthocyanidins (PACs) — a guarantee of stability and consistency;
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🌱 Comprehensive action: antioxidants, phenolic and organic acids work synergistically;
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🦠 Ex vivo studies show comparable or even stronger anti-E. coli effects than extracts with 20x more PACs.
🌍 Global Recognition of Pacran®
Pacran® has received regulatory approval in several countries:
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🇰🇷 South Korea (2009) — the first approved cranberry product for urinary health support;
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🇨🇦 Canada (2014) — approved for preventing recurrent UTIs in women;
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🇨🇴 Colombia (2015) — recognized as a product for managing recurrent UTIs;
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🇺🇸 USA (2020) — FDA issued a qualified health claim about whole cranberry powder reducing UTI risk in healthy women.
🧪 How Does It Work?
Pacran® acts not as an antibiotic, but as a natural barrier, blocking the ability of E. coli to adhere to the urinary tract lining. Without this step, bacteria cannot anchor and cause inflammation.
This effect is achieved through a synergistic mechanism involving all parts of the berry.
Pacran® is a clinically proven natural ingredient that:
✔ reduces the risk of recurrent UTIs
✔ is suitable for daily prevention
✔ is recognized and approved by international regulators
✔ has a strong scientific foundation
It can benefit both health-conscious consumers and healthcare professionals seeking reliable preventative solutions.
